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Sophie Rutschmann Selected Research

site 1 membrane-bound transcription factor peptidase

3/2011Hypomorphic mutation in the site-1 protease Mbtps1 endows resistance to persistent viral infection in a cell-specific manner.
3/2009Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response.

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Sophie Rutschmann Research Topics

Disease

5Infections
01/2015 - 12/2003
2Virus Diseases (Viral Diseases)
03/2011 - 06/2006
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
01/2018
1Prion Diseases (Transmissible Spongiform Encephalopathies)
08/2012
1Hypopigmentation (Hypomelanosis)
08/2012
1Scrapie
08/2012
1Hermanski-Pudlak Syndrome (Hermansky-Pudlak Syndrome)
11/2010
1Colitis
03/2009
1Inflammation (Inflammations)
09/2008
1Gram-Positive Bacterial Infections
12/2003

Drug/Important Bio-Agent (IBA)

3Proteins (Proteins, Gene)FDA Link
01/2015 - 01/2006
3Toll-Like Receptors (Toll-Like Receptor)IBA
11/2010 - 08/2005
3Ethylnitrosourea (N-Ethyl-N-nitrosourea)IBA
03/2009 - 08/2005
2site 1 membrane-bound transcription factor peptidaseIBA
03/2011 - 03/2009
1Complement System Proteins (Complement)IBA
01/2018
1AntigensIBA
01/2015
1Prion ProteinsIBA
08/2012
1CopperIBA
08/2012
1Peptide Hydrolases (Proteases)FDA Link
08/2012
1Dextrans (Dextran)FDA Link
03/2009
1sodium sulfate (sodium bisulfate)FDA LinkGeneric
03/2009
1Tyrosine (L-Tyrosine)FDA Link
09/2008
1Interleukin-1 (Interleukin 1)IBA
09/2008
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
09/2008
1VaccinesIBA
06/2006
1LipopolysaccharidesIBA
01/2006
1LipidsIBA
08/2005
1Toll-Like Receptor 2IBA
08/2005
1Carrier Proteins (Binding Protein)IBA
12/2003
1peptidoglycan recognition proteinIBA
12/2003

Therapy/Procedure

1Transplantation
06/2006